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AbstractPurpose: Universal cancer peptide-based vaccine (UCPVax) is a therapeutic vaccine composed of two highly...

Posted by : Dr. Dewi VERNEREY, Mme. Aurélia MEURISSE
Journal name : J Clin Oncol

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AbstractBackground: We evaluated the value of pre-treatment positron-emission tomography-computed tomography...

Posted by : Mme. Julie HENRIQUES, Mr. Antoine FALCOZ, Dr. Dewi VERNEREY
Journal name : Cancers (Basel)

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AbstractBackground: Overall response rate (ORR) and progression-free survival (PFS) are commonly used as endpoints...

Posted by : Dr. Dewi VERNEREY
Journal name : Clin Res Hepatol Gastroenterol

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AbstractPurpose: In patients with resectable gastric/gastroesophageal junction (GEJ) adenocarcinoma, surgery plus...

Posted by : Dr. Dewi VERNEREY, Mme. Julie HENRIQUES
Journal name : Journal of Clinical Oncology

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AbstractBackground: There is a strong rational of using anti-programmed cell death protein-1 and its ligand...

Posted by : Dr. Dewi VERNEREY, Mme. Aurélia MEURISSE
Journal name : Front Oncol

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AbstractNew combinations of antiangiogenic tyrosine kinase inhibitors (TKI) and immune checkpoint inhibitors (ICI) or...

Posted by : Dr. Guillaume MOUILLET
Journal name : Bulletin du cancer

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AbstractIntroduction: Regorafenib (R) and trifluridine/tipiracil (FTD/TPI) are of proven efficacy in metastatic...

Posted by : Mme. Julie HENRIQUES, Dr. Dewi VERNEREY
Journal name : Clinical colorectal cancer

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AbstractPurpose: This prospective pharmacokinetic (PK) ancillary study of the TEXCAN phase II GERCOR trial of...

Posted by : Mme. Julie HENRIQUES, Dr. Dewi VERNEREY
Journal name : European journal of cancer

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AbstractBackground: Red blood cell (RBC) transfusions are frequently required in the early period after kidney...

Posted by : Dr. Dewi VERNEREY, Mme. Aurélia MEURISSE
Journal name : Frontiers in oncology

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AbstractBackground: There is a paucity of data regarding the prognostic influence of peripheral blood CD4+ T...

Posted by : Dr. Dewi VERNEREY, Mme. Aurélia MEURISSE
Journal name : BMC cancer

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AbstractUntil recently, the first-line treatments used in metastatic renal cell carcinoma were based on first-generation...

Posted by : Dr. Guillaume MOUILLET
Journal name : Bulletin du cancer

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AbstractUntil recently, the first-line treatments used in metastatic renal cell carcinoma were based on first-generation...

Posted by : Dr. Guillaume MOUILLET
Journal name : Bulletin du cancer

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AbstractBackground: Histological characteristics at the invasive front may reflect tumor aggressiveness;...

Posted by : Mr. Antoine FALCOZ, Dr. Dewi VERNEREY
Journal name : Annals of oncology

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AbstractIntroduction: Survivors of viral ARDS are at risk of long-term physical, functional and neuropsychological...

Posted by : Mme. Aurélia MEURISSE, Dr. Dewi VERNEREY, Dr. Sophie PAGET-BAILLY
Journal name : Annals of Intensive Care

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AbstractBackground: Studies have reported a beneficial role of the addition of trastuzumab to platin-5-FU based...

Posted by : Mme. Julie HENRIQUES, Dr. Dewi VERNEREY
Journal name : Frontiers in oncology

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AbstractAim: To determine the safety of performing an anastomosis after rectal cancer (RC) resection in patients...

Posted by : Dr. Dewi VERNEREY, Mme. Aurélia MEURISSE
Journal name : Colorectal Dis

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AbstractBackground: Squamous cell carcinoma of the anus (SCCA) is a rare disease often diagnosed at a localised...

Posted by : Mme. Aurélia MEURISSE, Dr. Dewi VERNEREY
Journal name : Eur J Cancer

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AbstractIn the era of immune checkpoint inhibitors, understanding the metastatic microenvironment of proficient mismatch...

Posted by : Dr. Dewi VERNEREY
Journal name : Mol Oncol

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AbstractPurpose: Early-onset (EO) colorectal cancer (CRC, age < 50 years) incidence is increasing. Decisions on...

Posted by : Dr. Dewi VERNEREY
Journal name : J Clin Oncol

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AbstractBackground and objective: Longitudinal analysis of patient-reported outcome (PRO) data remains challenging,...

Posted by : Mr. Antoine FALCOZ
Journal name : Comput Methods Programs Biomed

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AbstractBackground: Adjuvant chemotherapy use in stage II colon cancer is controversial. Current prognostic risk...

Posted by : Dr. Dewi VERNEREY
Journal name : Cancers (Basel)

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AbstractHigh-risk HPV (hrHPV) testing has been implemented as a primary screening tool for cervical cancer in numerous...

Posted by : Mme. Julie HENRIQUES, Mme. Aurélia MEURISSE, Dr. Dewi VERNEREY, Dr. Sophie PAGET-BAILLY
Journal name : Cancers (Basel)

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AbstractBackground: Metastatic signet-ring cell colorectal carcinoma is rare. We analyzed its clinicopathological...

Posted by : , Mme. Aurélia MEURISSE, Dr. Dewi VERNEREY
Journal name : Dig Liver Dis

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AbstractAim: A systematic literature review of immuno-oncology trials was conducted to assess the potential impact of...

Posted by : Mr. Antoine FALCOZ, Dr. Guillaume MOUILLET
Journal name : Qual Life Res

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AbstractPurpose: Circulating tumor DNA (ctDNA) has been suggested as a major prognostic factor in resected stage...

Posted by : Mme. Julie HENRIQUES, Dr. Dewi VERNEREY
Journal name : Clin Cancer Res .

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AbstractBackground: Surgical resection with adjuvant chemotherapy is the only treatment that can provide long term...

Posted by : Dr. Dewi VERNEREY, Dr. Guillaume MOUILLET, Dr. Angélique VIENOT
Journal name : Front Oncol

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AbstractCirculating cell-free DNA (cfDNA) contains circulating tumor DNA (ctDNA), which can be obtained from serial...

Posted by : Mme. Julie HENRIQUES, Dr. Dewi VERNEREY
Journal name : Mol Oncol .

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AbstractBackground: Immune checkpoint inhibitors (ICIs) targeting the PD-1/PD-L1 axis have changed the first-line...

Posted by : Dr. Sophie PAGET-BAILLY
Journal name : Cochrane Database Syst Rev

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AbstractBackground: Team-based and timely integrated palliative care is a gold standard of care in oncology, but...

Posted by : Mme. Oumelkheir DJOUMAKH
Journal name : BMC Palliat Care .

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AbstractBackground: The Immunoscore (IS), which prognostically classifies stage I-III colon cancer (CC) patients,...

Posted by : Dr. Dewi VERNEREY, Mme. Julie HENRIQUES
Journal name : Ann Oncol

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AbstractBackground: The intensive care unit is increasingly recognized as a stressful environment for healthcare...

Posted by : Mme. Julie HENRIQUES, Dr. Sophie PAGET-BAILLY
Journal name : Ann Intensive Care .

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AbstractBackground: Ageing is associated with an increased prevalence of comorbidities and sarcopenia as well as a...

Posted by : Dr. Sophie PAGET-BAILLY
Journal name : BMJ Open

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AbstractKeywords: RTQA; chemoradiotherapy; locally advanced; pancreatic adenocarcinoma; quality control; radiation...

Posted by : Dr. Dewi VERNEREY
Journal name : Int J Radiat Oncol Biol Phys

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AbstractPurpose: Baseline neutrophil count may predict overall survival (OS) in patients with locally advanced...

Posted by : Dr. Dewi VERNEREY, Pr. Franck BONNETAIN
Journal name : Int J Radiat Oncol Biol Phys

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AbstractSmall bowel adenocarcinoma (SBA) is a rare tumour. Large genomic analyses with prognostic assessments are...

Posted by : Mme. Julie HENRIQUES, Dr. Dewi VERNEREY
Journal name : Int J Cancer

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AbstractAims: The addition of docetaxel to cisplatin and 5-fluorouracil (DCF) has shown promising efficacy in...

Posted by : Mme. Aurélia MEURISSE, Dr. Dewi VERNEREY
Journal name : Ther Adv Med Oncol

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AbstractBackground: The IMMUNOBIL PRODIGE 57 trial is a non-comparative randomized phase II study assessing the...

Posted by : Dr. Dewi VERNEREY
Journal name : Eur J Cancer

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AbstractFluoropyrimidine (FP) plus platinum chemotherapy has been recently established as a second-line (L2) preferred...

Posted by : Dr. Angélique VIENOT, Mme. Aurélia MEURISSE, Dr. Dewi VERNEREY
Journal name : Int J Cancer

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AbstractBackground: A prospective, pooled analysis of six randomised phase 3 trials was done to investigate...

Posted by : Dr. Dewi VERNEREY
Journal name : Lancet Oncol

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AbstractIntroduction - Routine Electronic Monitoring of Health-Related Quality of Life (HRQoL) (REMOQOL) in clinical...

Posted by : Dr. Guillaume MOUILLET, Mr. Antoine FALCOZ, Mme. Joëlle FRITZSCH, , Mme. Oumelkheir DJOUMAKH, Dr. Sophie PAGET-BAILLY
Journal name : Quality of Life Research

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In their recent article in Journal of Clinical Oncology regarding the InterAAct phase II trial in advanced...

Posted by : Dr. Dewi VERNEREY
Journal name : J Clin Oncol

AbstractBackground: Randomized controlled trials (RCTs) represent the best evidence in oncology research....

Posted by : Mr. Antoine FALCOZ, Dr. Sophie PAGET-BAILLY, Dr. Dewi VERNEREY
Journal name : Neurooncol Pract

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AbstractBackground: Immune checkpoint inhibitors (ICIs) are highly effective in patients with microsatellite...

Posted by : Mme. Aurélia MEURISSE, Dr. Dewi VERNEREY
Journal name : J Immunother Cancer

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AbstractSmall bowel adenocarcinoma (SBA) is a rare tumour. We conducted a prospective cohort to describe the prevalence,...

Posted by : Mme. Julie HENRIQUES, Dr. Dewi VERNEREY
Journal name : Int J Cancer

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AbstractIn metastatic pancreatic adenocarcinoma, a high neutrophil-to-lymphocyte ratio (NLR) at diagnosis is a marker of...

Posted by : Mme. Julie HENRIQUES, Dr. Dewi VERNEREY
Journal name : Clin Res Hepatol Gastroenterol

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AbstractImportance: In the pivotal Bevacizumab-Avastin Adjuvant (AVANT) trial, patients with high-risk stage II...

Posted by : Mme. Julie HENRIQUES
Journal name : JAMA Netw Open .

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AbstractBackground: While open-label randomized controlled trials (RCT) are common in oncology, some concerns have...

Posted by : Dr. Guillaume MOUILLET
Journal name : Cancer Med

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AbstractDocetaxel, cisplatin and 5-fluorouracil (DCF) chemotherapy regimen is highly effective in advanced anal squamous...

Posted by : Dr. Angélique VIENOT, Dr. Dewi VERNEREY, Mme. Aurélia MEURISSE
Journal name : Int J Mol Sci

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AbstractBackground: Our study describes the feasibility and efficacy of a first-line FOLFIRINOX (5-fluorouracil...

Posted by : Dr. Dewi VERNEREY, Mme. Aurélia MEURISSE
Journal name : Oncologist

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AbstractAim: Raltitrexed (RTX) is a thymidylate synthase inhibitor with large pharmacokinetics (PK) variability...

Posted by : Dr. Dewi VERNEREY, Mme. Julie HENRIQUES
Journal name : Br J Clin Pharmacol

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AbstractMismatch repair-deficient (dMMR) and/or microsatellite instability-high (MSI) colorectal cancers (CRC) represent...

Posted by : Dr. Dewi VERNEREY, Mme. Julie HENRIQUES
Journal name : Int J Cancer

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Background: Despite its proven efficacy in reducing recurrence and improving survival, adherence to endocrine...

Posted by : Dr. Sophie PAGET-BAILLY
Journal name : Trials

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AbstractBackground: Synchronous prostate cancer (PC) and rectal cancer (RC) is a rare clinical situation. While...

Posted by : Dr. Dewi VERNEREY, Mme. Aurélia MEURISSE
Journal name : Ann Surg Oncol

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AbstractBackground Metastatic Squamous cell Penile Carcinoma (mSCPC) is an orphan disease with a virally induced...

Posted by : Dr. Guillaume MOUILLET, Dr. Dewi VERNEREY, Mme. Aurélia MEURISSE
Journal name : Bull Cancer

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AbstractBackground: Preoperative radiochemotherapy (RCT) is recommended in France prior to total mesorectal...

Posted by : Dr. Dewi VERNEREY
Journal name : BMC Cancer

AbstractBackground: Patients with severe renal impairment or undergoing hemodialysis are usually excluded from...

Posted by : Dr. Guillaume MOUILLET
Journal name : Semin Oncol

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AbstractPatients and methods: A post hoc analysis of all pathologic reports from patients with stage III CC...

Posted by : Mme. Julie HENRIQUES, Mr. Antoine FALCOZ, Dr. Dewi VERNEREY
Journal name : J Clin Oncol

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AbstractAnti-EGFR efficacy in patients with microsatellite instability (MSI) metastatic colorectal cancer (mCRC)...

Posted by : Mme. Julie HENRIQUES, Dr. Dewi VERNEREY
Journal name : J Natl Cancer Inst

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AbstractBackground: Modified docetaxel, cisplatin, and 5-fluorouracil (mDCF) regimen has become a new standard for the...

Posted by : Dr. Dewi VERNEREY
Journal name : BMC Cancer

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AbstractPurpose: The aim of this study was to investigate the association between expression of insulin-like growth...

Posted by : Mme. Julie HENRIQUES
Journal name : Cell Oncol (Dordr)

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AbstractBackground: FOLFIRINOX regimen is the first-line reference chemotherapy (L1) in advanced pancreatic ductal...

Posted by : Dr. Angélique VIENOT, Dr. Dewi VERNEREY
Journal name : World J Gastrointest Oncol

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AbstractKeywords: Adjuvant; Chemotherapy; Colon cancer; Guidelines; Randomised controlled trials; Time-to-event...

Posted by : Dr. Dewi VERNEREY, Mme. Aurélia MEURISSE, Mme. Julie HENRIQUES
Journal name : Eur J Cancer

AbstractBackground: Despite improvement in colorectal liver metastasis (CLM) treatment, survival after liver...

Posted by : Dr. Dewi VERNEREY
Journal name : Ann Surg Oncol

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AbstractBackground: Although no data have been reported beyond second-line therapy, aflibercept is approved in this...

Posted by : Dr. Dewi VERNEREY
Journal name : Clin Colorectal Cancer

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AbstractIntroduction: Perioperative chemotherapy is the standard strategy for localized gastric cancers....

Posted by : Dr. Dewi VERNEREY
Journal name : Bull Cancer

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AbstractBackground: The bevacizumab-Avastin® adjuVANT (AVANT) study did not meet its primary end point of...

Posted by : Dr. Dewi VERNEREY
Journal name : Ann Oncol .

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AbstractBackground: Patients with RAS wild-type (WT) nonresectable metastatic colorectal cancer (mCRC) may receive...

Posted by : Mme. Julie HENRIQUES, Dr. Dewi VERNEREY
Journal name : Oncologist

AbstractBackground: The use of absorbable meshes during contaminated or infected incisional hernia (IH) repair is...

Posted by : Mme. Julie HENRIQUES
Journal name : J Gastrointest Surg

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AbstractBackground: To evaluate the objective response rate (ORR) at 2 months of treatment with regorafenib...

Posted by : Mme. Julie HENRIQUES
Journal name : Cancer Imaging

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AbstractBackground: FOLFIRINOX (leucovorin, 5-fluorouracil, irinotecan, and oxaliplatin) is an option for fit...

Posted by : Dr. Dewi VERNEREY, Mme. Aurélia MEURISSE
Journal name : Clin Colorectal Cancer

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AbstractBACKGROUND:Recurrence patterns in stage III colon cancer (CC) patients according to molecular markers remain...

Posted by : Dr. Dewi VERNEREY,
Journal name : Ann Surg Oncol.

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AbstractBACKGROUND:Adjuvant treatment for stage II colon cancer (CC) can be proposed to patients with high-risk disease....

Posted by : Dr. Dewi VERNEREY
Journal name : Br J Cancer

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AbstractBACKGROUND:Despite the critical roles of Th1-polarised CD4+ T cells in cancer immunosurveillance, the...

Posted by : Dr. Dewi VERNEREY
Journal name : Br J Cancer.

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AbstractPURPOSE:Defective mismatch repair system (dMMR) has been shown to have a favorable impact on outcome in patients...

Posted by : Dr. Dewi VERNEREY
Journal name : Int J Radiat Oncol Biol Phys

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AbstractBACKGROUND:We explored and validated the association of postoperative carcinoembryonic antigen (CEA) with...

Posted by : Dr. Dewi VERNEREY
Journal name : Cancer Epidemiol Biomarkers Prev

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AbstractIn patients with metastatic colorectal cancer (mCRC), RAS and BRAF mutations are currently determined by tumor...

Posted by : Dr. Dewi VERNEREY, Mme. Aurélia MEURISSE
Journal name : Cancers

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AbstractBACKGROUND:Specific surgical and oncological outcomes in patients with rectal cancer surgery after a previous...

Posted by : Dr. Dewi VERNEREY, Mme. Aurélia MEURISSE
Journal name : Br J Surg

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AbstractBackground: In 2013, the interim analysis of the Protocol for Herceptin as Adjuvant therapy with Reduced...

Posted by : Dr. Sophie PAGET-BAILLY, Mme. Julie HENRIQUES
Journal name : Lancet

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AbstractINTRODUCTION:The demographics of oncology residents has changed since 2010 with the increase in the size of...

Posted by : Dr. Dewi VERNEREY
Journal name : Bull Cancer

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AbstractBACKGROUND:Post-transplant diabetes is a frequent and serious complication of kidney transplantation. There is...

Posted by : Dr. Dewi VERNEREY
Journal name : Trials

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AbstractBackground: Failed kidney transplant is becoming a frequent cause of dialysis initiation. Although studies...

Posted by : Mme. Julie HENRIQUES, Dr. Dewi VERNEREY
Journal name : Nephrol Dial Transplant

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AbstractBACKGROUND:The benefit of second-line chemotherapy (L2) over standard first-line (L1) gemcitabine plus cisplatin...

Posted by : Dr. Dewi VERNEREY, Mme. Aurélia MEURISSE
Journal name : Eur J Cancer.

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AbstractBACKGROUND:About 5% of pancreatic ductal adenocarcinomas are inherited due to a deleterious germline mutation...

Posted by : Dr. Dewi VERNEREY
Journal name : United European Gastroenterol

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AbstractAflibercept in combination with 5‑fluorouracil (5‑FU)/irinotecan improves overall survival in the...

Posted by : Mme. Aurélia MEURISSE, Pr. Franck BONNETAIN
Journal name : Int J Oncol .

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AbstractPurpose: Human papillomavirus (HPV) is found in 90% of squamous cell carcinomas of the anal canal (SCCA)....

Posted by : Mme. Aurélia MEURISSE
Journal name : Clin Cancer Res .

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ABSTRACTBACKGROUND: Two main therapies, pazopanib and sunitinib, are used in the first-line setting for metastatic renal...

Posted by : Dr. Guillaume MOUILLET, Mme. Joëlle FRITZSCH, Dr. Sophie PAGET-BAILLY, , Mme. Aurélia MEURISSE, Dr. Dewi VERNEREY, Pr. Franck BONNETAIN
Journal name : Health and Quality of Life Outcomes

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AbstractObjective: To evaluate the effects of switching from prednisone (P) to dexamethasone (D) at asymptomatic...

Posted by : Mme. Julie HENRIQUES, Pr. Franck BONNETAIN
Journal name : BJU Int

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ABSTRACTDespite the importance of metastatic clear-cell renal cell carcinoma, studies on its economic burden in daily...

Posted by : , Dr. Guillaume MOUILLET
Journal name : Clinical Genitourinary Cancer

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AbstractThe objective of this study was to assess the psychometric properties of the French version of the Supportive...

Posted by : Pr. Franck BONNETAIN
Journal name : European Journal of Cancer Care

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AbstractBackgroundNivolumab-ipilimumab demonstrated a survival benefit over sunitinib in first-line setting for...

Posted by : , Dr. Guillaume MOUILLET
Journal name : European Journal of Cancer

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AbstractBackground: 5-Fluorouracil (5-FU) and platinum-based perioperative chemotherapy is standard of care for...

Posted by : Mme. Aurélia MEURISSE
Journal name : Eur J Cancer

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AbstractPurpose The inclusion of patient-reported outcome (PRO) questionnaires in prognostic factor analyses in...

Posted by : Pr. Franck BONNETAIN
Journal name : Quality of Life Research

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ABSTRACTIntroductionWhile there is mounting evidence of the independent prognostic value of patient-reported outcomes...

Posted by : Pr. Franck BONNETAIN
Journal name : BMJ Open

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AbstractBACKGROUND:The incidence of anal squamous cell carcinoma has been increasing markedly in the past few decades....

Posted by : Pr. Franck BONNETAIN, Mme. Aurélia MEURISSE, Dr. Dewi VERNEREY
Journal name : Lancet Oncol

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AbstractBACKGROUND:At time of diagnosis, less than 10% of patients with pancreatic adenocarcinomas (PDAC) are considered...

Posted by : Dr. Dewi VERNEREY
Journal name : BMC Cancer

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AbstractBACKGROUND:The incidence of anal squamous cell carcinoma has been increasing markedly in the past few decades....

Posted by : Pr. Franck BONNETAIN, Mme. Aurélia MEURISSE, Dr. Dewi VERNEREY
Journal name : Lancet Oncol

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ABSTRACTBackground: Cardiac toxicity with a decrease of the left ventricular ejection fraction (LVEF) is the main side...

Posted by : Dr. Sophie PAGET-BAILLY, Mme. Julie HENRIQUES
Journal name : The Breast

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Letter to editor.LINK

Posted by : Pr. Franck BONNETAIN, Dr. Dewi VERNEREY
Journal name : European Journal of Cancer

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ABSTRACTBackgroundSunitinib is a tyrosine kinase inhibitor approved in the first-line metastatic renal cell carcinoma...

Posted by : Dr. Guillaume MOUILLET, Mme. Aurélia MEURISSE, Dr. Dewi VERNEREY
Journal name : Trials

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BACKGROUND:Since 2004, a regimen of 6 months of treatment with oxaliplatin plus a fluoropyrimidine has been standard...

Posted by : Dr. Dewi VERNEREY
Journal name : New England Journal of Medicine

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ABSTRACTPurpose Reduction of adjuvant treatment duration may decrease toxicities without loss of efficacy in stage III...

Posted by : Dr. Dewi VERNEREY, Dr. Sophie PAGET-BAILLY, Pr. Franck BONNETAIN
Journal name : Journal of Clinical Oncology

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BACKGROUND:RAS mutations are currently sought for in tumor samples, which takes a median of almost 3 weeks in western...

Posted by : Dr. Dewi VERNEREY, Pr. Franck BONNETAIN, Mme. Aurélia MEURISSE
Journal name : Ann Oncol

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BACKGROUND:Expression of SRY [sex-determining region Y]-box11 (SOX11) is specific to mantle cell lymphoma (MCL) and...

Posted by : Dr. Dewi VERNEREY
Journal name : Exp Hematol Oncol

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ABSTRACTBackground and objective: Health-related quality of life (HRQoL) has become one relevant and available...

Posted by : Pr. Franck BONNETAIN
Journal name : Computer Methods and Programs in Biomedicine

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With advances in breast cancer (BC) gene panel testing, risk counseling has become increasingly complex, potentially...

Posted by : Pr. Franck BONNETAIN
Journal name : International Journal of Environmental Research and Public Health

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PurposeThe aim of this study was to determine the prevalence of adherence to adjuvant hormonal therapy (AHT) and to...

Posted by : Mme. Julie HENRIQUES, Dr. Sophie PAGET-BAILLY
Journal name : Breast Cancer Research and Treatment

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BackgroundPatients treated with chemotherapy for microsatellite unstable (MSI) and/or mismatch repair deficient (dMMR)...

Posted by : Dr. Dewi VERNEREY
Journal name : Eur J Cancer

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AbstractBACKGROUND:Current prognostic systems for myelodysplastic syndromes (MDS) are based on clinical, pathologic, and...

Posted by : Pr. Franck BONNETAIN
Journal name : Cancer

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AbstractBackgroundWe studied the relationship between intermediate criteria and overall survival (OS) in metastatic...

Posted by : Dr. Sophie PAGET-BAILLY, Pr. Franck BONNETAIN
Journal name : Clinical Colorectal Cancer

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Advances in cancer care delivery require revision and further development of questionnaires assessing patients’...

Posted by : Pr. Franck BONNETAIN
Journal name : European Journal of Cancer Care

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AbstractBackground: Genome-wide association studies (GWAS) have to date identified 94 genetic variants (single...

Posted by : Mme. Julie HENRIQUES, Dr. Sophie PAGET-BAILLY
Journal name : Breast Cancer Research

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Abstract Background  The overexpression of human epidermal growth factor receptor-2 (HER2) in breast cancer is a...

Posted by : Pr. Franck BONNETAIN, Dr. Dewi VERNEREY
Journal name : BMC Cancer

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We conducted a retrospective study to assess the follow-up of patients with localized breast cancer and the first...

Posted by : Mme. Aurélia MEURISSE,
Journal name : Breast

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AbstractAim: Adjuvant clinical trials in early human epidermal growth factor receptor 2 (HER2)-positive breast cancer...

Posted by : Mme. Julie HENRIQUES, Dr. Sophie PAGET-BAILLY
Journal name : European Journal of Cancer

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Since the MOSAIC study, oxaliplatin-based adjuvant chemotherapy has been the standard treatment of stage III colon...

Posted by : Dr. Dewi VERNEREY, Pr. Franck BONNETAIN
Journal name : Annals of Oncology

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Background: In advanced pancreatic ductal adenocarcinoma (aPDAC), there is no consensual strategy for second-line...

Posted by : Dr. Angélique VIENOT, Dr. Dewi VERNEREY, Pr. Franck BONNETAIN, Mme. Aurélia MEURISSE
Journal name : JNCI J Natl Cancer Inst

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AbstractTraditionally, the efficacy of cancer treatment in patients with advance or metastatic disease in clinical...

Posted by : Pr. Franck BONNETAIN
Journal name : Annals of Oncology

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ABSTRACTIntroduction: Intermediate endpoints are often used as primary endpoints instead of overall survival (OS) in...

Posted by : Pr. Franck BONNETAIN
Journal name : Expert Review of Anticancer Therapy

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Background:To assess the efficacy of a patient educational program built according to guidelines that aims at reducing...

Posted by : Pr. Franck BONNETAIN
Journal name : British Journal of Cancer

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Background Nab-paclitaxel plus gemcitabine has become a standard treatment regimen in patients with metastatic...

Posted by : Mme. Aurélia MEURISSE, Pr. Franck BONNETAIN
Journal name : Lancet Gastroenterology Hepatology

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BackgroundEven if a large majority of out-of-hospital cardiac arrest (OHCA) survivors appear to have a good neurological...

Posted by : Pr. Franck BONNETAIN
Journal name : Resuscitation

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The measurement of the quality of life in terms of health of people undergoing treatment for cancer is developing. Th is...

Posted by : Pr. Franck BONNETAIN, Dr. Sophie PAGET-BAILLY, Mme. Joëlle FRITZSCH, Dr. Guillaume MOUILLET
Journal name : La revue de l'infirmière

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SummaryData in the literature regarding the care pathway of pancreatic cancer patients are limited. The objective of the...

Posted by : Pr. Franck BONNETAIN
Journal name : Bulletin du Cancer

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Background: Medical progress and the lifestyle modification have prolonged life expectancy, despite the development of...

Posted by : , Pr. Franck BONNETAIN
Journal name : Trials

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AbstractBackground:Frailty is highly prevalent in elderly people. While significant progress has been made to...

Posted by : Dr. Dewi VERNEREY, Dr. Sophie PAGET-BAILLY, , Pr. Franck BONNETAIN
Journal name : BMC Geriatrics

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AbstractBackground:Pancreatic adenocarcinoma (PDAC) incidence is increasing worldwide. Several studies have shown...

Posted by : Dr. Dewi VERNEREY, Pr. Franck BONNETAIN
Journal name : BMC Cancer

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Docetaxel, cisplatin, and 5-fluorouracil (DCF) significantly improved overall survival in metastatic gastroesophageal...

Posted by : Pr. Franck BONNETAIN, Dr. Sophie PAGET-BAILLY
Journal name : Cancer Medecine

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Measures of health-related quality of life (HRQOL) and other patient-reported outcomes generate important data in cancer...

Posted by : Pr. Franck BONNETAIN
Journal name : Lancet Oncology

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AbstractTemozolomide (TEM) showed encouraging results in well-differentiated pancreatic neuroendocrine tumors (WDPNETs)....

Posted by : Dr. Dewi VERNEREY
Journal name : Endocrine-Related Cancer

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AbstractThe diagnosis system for allograft loss lacks accurate individual risk stratification on the basis of...

Posted by : Dr. Dewi VERNEREY
Journal name : J Am Soc Nephrol

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In first-line metastatic colorectal cancer (mCRC), baseline prognostic factors allowing death risk and treatment...

Posted by : Dr. Dewi VERNEREY, Pr. Franck BONNETAIN
Journal name : International Journal of Cancer

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Background:The management of locally advanced pancreatic cancer (LAPC) patients remains controversial. Better...

Posted by : Dr. Dewi VERNEREY, Dr. Angélique VIENOT, Pr. Franck BONNETAIN
Journal name : British Journal of Cancer

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Our aim was to review the studies which assessed potential surrogate endpoints for overall survival (OS) in breast...

Posted by : Pr. Franck BONNETAIN,
Journal name : Breast

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In the Intergroupe Francophone de Cancérologie Thoracique 0501 trial the carboplatinpaclitaxel chemotherapy increased...

Posted by : Pr. Franck BONNETAIN
Journal name : European Respiratory Journal

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Background: Even though the perioperative chemotherapy improves the overall survival (OS) compared to surgery alone in...

Posted by : Dr. Sophie PAGET-BAILLY, , Pr. Franck BONNETAIN
Journal name : European Journal of Surgical Oncology

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PurposeWe previously showed that a sequential chemotherapy with dose-dense oxaliplatin (FOLFOX7)and irinotecan (FOLFIRI;...

Posted by : Pr. Franck BONNETAIN
Journal name : PLOS ONE

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AbstractGlioblastoma is the most common malignant brain tumor in adults. Baselinehealth-relatedquality of life (HRQoL)...

Posted by : , Dr. Dewi VERNEREY, , Pr. Franck BONNETAIN
Journal name : Cancer Medicine

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OBJECTIVES: The objective of this study was to explore the association between health-related quality of life (HRQoL)...

Posted by : , Pr. Franck BONNETAIN
Journal name : BMJ Open

OBJECTIVES: We conducted a prospective study approved by the local ethics committee to determine the impact of a...

Posted by : Pr. Franck BONNETAIN
Journal name : Annales pharmaceutiques françaises

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IMPORTANCE In locally advanced pancreatic cancer, the role of chemoradiotherapy is controversial and the efficacy of...

Posted by : Pr. Franck BONNETAIN
Journal name : JAMA

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Health-related quality of life (HRQOL) in cancer research is critical to more comprehensively evaluate patients’...

Posted by : Pr. Franck BONNETAIN, ,
Journal name : Journal of Clinical Oncology

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AbstractBackground: Health-related quality of life (HRQoL) is recognized as a component endpoint for cancer...

Posted by : Pr. Franck BONNETAIN
Journal name : BMC Cancer

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Background: Deficient mismatch repair (dMMR) colon cancer (CC) is reportedly resistant to 5-fluorouracil (5FU) adjuvant...

Posted by : Dr. Guillaume MOUILLET, Dr. Dewi VERNEREY, Pr. Franck BONNETAIN
Journal name : JNCI Journal of the National Cancer Institure

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AbstractBACKGROUND:We investigated whether the health-related quality of life (HRQoL) score is a prognostic factor for...

Posted by : Pr. Franck BONNETAIN, Dr. Dewi VERNEREY
Journal name : EJC

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Purpose Eastern Cooperative Oncology Group Performance Status (ECOG-PS) is currently an important parameter in the...

Posted by : Pr. Franck BONNETAIN
Journal name : Quality of Life Research

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AbstractPURPOSE:The MOSAIC (Multicenter International Study of Oxaliplatin/Fluorouracil/Leucovorin in the Adjuvant...

Posted by : Dr. Dewi VERNEREY, Pr. Franck BONNETAIN
Journal name : JCO

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AbstractBACKGROUND:The combination of an anti-VEGF or an anti-EGFR-targeted monoclonal antibody with chemotherapy has...

Posted by : Dr. Dewi VERNEREY, Pr. Franck BONNETAIN
Journal name : Lancet Oncol

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ABSTRACT Rationale:The role of circulating antibodies in addition to traditional cardiovascular risk factors in...

Posted by : Dr. Dewi VERNEREY
Journal name : Test

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AbstractOBJECTIVES:To assess the long term outcomes of transplantation using expanded criteria donors (ECD; donors aged...

Posted by : Dr. Dewi VERNEREY
Journal name : BMJ

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AbstractAIM:Microarray studies identified a subgroup of molecular apocrine tumors (estrogen receptor [ER]...

Posted by : Dr. Dewi VERNEREY
Journal name : Future Oncol

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Abstract Background: Baseline prognostic biomarkers stratifying treatment strategies in first-line metastatic...

Posted by : Pr. Franck BONNETAIN, Dr. Dewi VERNEREY
Journal name :

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BACKGROUND:A randomized multicenter phase II trial was conducted to assess the sequential treatment strategy using...

Posted by : Pr. Franck BONNETAIN, Dr. Guillaume MOUILLET, Dr. Sophie PAGET-BAILLY
Journal name : PlosOne

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AbstractOverall survival (OS) has been considered as the most relevant primary endpoint but trials using OS often...

Posted by : Pr. Franck BONNETAIN, Dr. Dewi VERNEREY, Dr. Sophie PAGET-BAILLY
Journal name : Expert Review of Anticancer Therapy

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