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ABSTRACTBACKGROUND: Two main therapies, pazopanib and sunitinib, are used in the first-line setting for metastatic renal...

Posted by : Dr. Guillaume MOUILLET, Mme. Joëlle FRITZSCH, Dr. Sophie PAGET-BAILLY, Mme. Astrid POZET, Mme. Ikram ES-SAAD, Mme. Aurélia MEURISSE, Dr. Dewi VERNEREY, Pr. Franck BONNETAIN, Dr. Amélie ANOTA
Journal name : Health and Quality of Life Outcomes

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ABSTRACTDespite the importance of metastatic clear-cell renal cell carcinoma, studies on its economic burden in daily...

Posted by : Dr. Amélie ANOTA, Dr. Guillaume MOUILLET
Journal name : Clinical Genitourinary Cancer

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AbstractThe objective of this study was to assess the psychometric properties of the French version of the Supportive...

Posted by : Dr. Amélie ANOTA, Pr. Franck BONNETAIN
Journal name : European Journal of Cancer Care

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AbstractBackgroundNivolumab-ipilimumab demonstrated a survival benefit over sunitinib in first-line setting for...

Posted by : Dr. Edouard AUCLIN, Dr. Guillaume MOUILLET
Journal name : European Journal of Cancer

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AbstractPurpose The inclusion of patient-reported outcome (PRO) questionnaires in prognostic factor analyses in...

Posted by : Dr. Amélie ANOTA, Pr. Franck BONNETAIN
Journal name : Quality of Life Research

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ABSTRACTIntroductionWhile there is mounting evidence of the independent prognostic value of patient-reported outcomes...

Posted by : Dr. Amélie ANOTA
Journal name : BMJ Open

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AbstractBACKGROUND:The incidence of anal squamous cell carcinoma has been increasing markedly in the past few decades....

Posted by : Dr. Amélie ANOTA, Mme. Aurélia MEURISSE, Dr. Dewi VERNEREY
Journal name : Lancet Oncol

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AbstractBACKGROUND:At time of diagnosis, less than 10% of patients with pancreatic adenocarcinomas (PDAC) are considered...

Posted by : Dr. Dewi VERNEREY
Journal name : BMC Cancer

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ABSTRACTBackground: Cardiac toxicity with a decrease of the left ventricular ejection fraction (LVEF) is the main side...

Posted by : Dr. Sophie PAGET-BAILLY, Mme. Julie HENRIQUES
Journal name : The Breast

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Letter to editor.LINK

Posted by : Dr. Edouard AUCLIN, Dr. Dewi VERNEREY
Journal name : European Journal of Cancer

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ABSTRACTBackgroundSunitinib is a tyrosine kinase inhibitor approved in the first-line metastatic renal cell carcinoma...

Posted by : Dr. Guillaume MOUILLET, Mme. Aurélia MEURISSE, Dr. Dewi VERNEREY
Journal name : Trials

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BACKGROUND:Since 2004, a regimen of 6 months of treatment with oxaliplatin plus a fluoropyrimidine has been standard...

Posted by : Dr. Dewi VERNEREY
Journal name : New England Journal of Medicine

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ABSTRACTPurpose Reduction of adjuvant treatment duration may decrease toxicities without loss of efficacy in stage III...

Posted by : Dr. Dewi VERNEREY, Dr. Sophie PAGET-BAILLY, Pr. Franck BONNETAIN
Journal name : Journal of Clinical Oncology

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BACKGROUND:RAS mutations are currently sought for in tumor samples, which takes a median of almost 3 weeks in western...

Posted by : Dr. Dewi VERNEREY, Pr. Franck BONNETAIN, Mme. Aurélia MEURISSE
Journal name : Ann Oncol

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BACKGROUND:Expression of SRY [sex-determining region Y]-box11 (SOX11) is specific to mantle cell lymphoma (MCL) and...

Posted by : Dr. Dewi VERNEREY
Journal name : Exp Hematol Oncol

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ABSTRACTBackground and objective: Health-related quality of life (HRQoL) has become one relevant and available...

Posted by : Dr. Amélie ANOTA, Pr. Franck BONNETAIN
Journal name : Computer Methods and Programs in Biomedicine

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With advances in breast cancer (BC) gene panel testing, risk counseling has become increasingly complex, potentially...

Posted by : Dr. Amélie ANOTA
Journal name : International Journal of Environmental Research and Public Health

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PurposeThe aim of this study was to determine the prevalence of adherence to adjuvant hormonal therapy (AHT) and to...

Posted by : Mme. Julie HENRIQUES, Dr. Sophie PAGET-BAILLY, Dr. Amélie ANOTA
Journal name : Breast Cancer Research and Treatment

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BackgroundPatients treated with chemotherapy for microsatellite unstable (MSI) and/or mismatch repair deficient (dMMR)...

Posted by : Dr. Dewi VERNEREY
Journal name : Eur J Cancer

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AbstractBACKGROUND:Current prognostic systems for myelodysplastic syndromes (MDS) are based on clinical, pathologic, and...

Posted by : Dr. Amélie ANOTA, Pr. Franck BONNETAIN
Journal name : Cancer

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AbstractBackgroundWe studied the relationship between intermediate criteria and overall survival (OS) in metastatic...

Posted by : Dr. Sophie PAGET-BAILLY, Pr. Franck BONNETAIN
Journal name : Clinical Colorectal Cancer

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Advances in cancer care delivery require revision and further development of questionnaires assessing patients’...

Posted by : Dr. Amélie ANOTA, Pr. Franck BONNETAIN
Journal name : European Journal of Cancer Care

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AbstractBackground: Genome-wide association studies (GWAS) have to date identified 94 genetic variants (single...

Posted by : Mme. Julie HENRIQUES, Dr. Sophie PAGET-BAILLY
Journal name : Breast Cancer Research

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Abstract Background  The overexpression of human epidermal growth factor receptor-2 (HER2) in breast cancer is a...

Posted by : Pr. Franck BONNETAIN, Dr. Dewi VERNEREY
Journal name : BMC Cancer

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We conducted a retrospective study to assess the follow-up of patients with localized breast cancer and the first...

Posted by : Mme. Aurélia MEURISSE,
Journal name : Breast

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AbstractAim: Adjuvant clinical trials in early human epidermal growth factor receptor 2 (HER2)-positive breast cancer...

Posted by : Mme. Julie HENRIQUES, Dr. Sophie PAGET-BAILLY
Journal name : European Journal of Cancer

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Background: In advanced pancreatic ductal adenocarcinoma (aPDAC), there is no consensual strategy for second-line...

Posted by : Dr. Dewi VERNEREY, Pr. Franck BONNETAIN, Mme. Aurélia MEURISSE
Journal name : JNCI J Natl Cancer Inst

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Since the MOSAIC study, oxaliplatin-based adjuvant chemotherapy has been the standard treatment of stage III colon...

Posted by : Dr. Dewi VERNEREY, Pr. Franck BONNETAIN
Journal name : Annals of Oncology

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AbstractTraditionally, the efficacy of cancer treatment in patients with advance or metastatic disease in clinical...

Posted by : Pr. Franck BONNETAIN
Journal name : Annals of Oncology

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ABSTRACTIntroduction: Intermediate endpoints are often used as primary endpoints instead of overall survival (OS) in...

Posted by : , Pr. Franck BONNETAIN
Journal name : Expert Review of Anticancer Therapy

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Background:To assess the efficacy of a patient educational program built according to guidelines that aims at reducing...

Posted by : Dr. Amélie ANOTA, Pr. Franck BONNETAIN
Journal name : British Journal of Cancer

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Background Nab-paclitaxel plus gemcitabine has become a standard treatment regimen in patients with metastatic...

Posted by : Mme. Aurélia MEURISSE, Pr. Franck BONNETAIN
Journal name : Lancet Gastroenterology Hepatology

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BackgroundEven if a large majority of out-of-hospital cardiac arrest (OHCA) survivors appear to have a good neurological...

Posted by : Pr. Franck BONNETAIN
Journal name : Resuscitation

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The measurement of the quality of life in terms of health of people undergoing treatment for cancer is developing. Th is...

Posted by : Mme. Ikram ES-SAAD, Dr. Sophie PAGET-BAILLY, Mme. Joëlle FRITZSCH, Dr. Guillaume MOUILLET, Pr. Franck BONNETAIN
Journal name : La revue de l'infirmière

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SummaryData in the literature regarding the care pathway of pancreatic cancer patients are limited. The objective of the...

Posted by : Pr. Franck BONNETAIN
Journal name : Bulletin du Cancer

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Background: Medical progress and the lifestyle modification have prolonged life expectancy, despite the development of...

Posted by : Mme. Astrid POZET, Mme. Audrey FOUBERT, Mme. Morgane CHOTARD, Dr. Amélie ANOTA, Pr. Franck BONNETAIN
Journal name : Trials

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AbstractBackground:Frailty is highly prevalent in elderly people. While significant progress has been made to...

Posted by : Dr. Dewi VERNEREY, Dr. Amélie ANOTA, Dr. Sophie PAGET-BAILLY, Mme. Audrey FOUBERT, Mme. Astrid POZET, Pr. Franck BONNETAIN
Journal name : BMC Geriatrics

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AbstractBackground:Pancreatic adenocarcinoma (PDAC) incidence is increasing worldwide. Several studies have shown...

Posted by : Dr. Dewi VERNEREY, Pr. Franck BONNETAIN
Journal name : BMC Cancer

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Measures of health-related quality of life (HRQOL) and other patient-reported outcomes generate important data in cancer...

Posted by : Pr. Franck BONNETAIN
Journal name : Lancet Oncology

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Docetaxel, cisplatin, and 5-fluorouracil (DCF) significantly improved overall survival in metastatic gastroesophageal...

Posted by : , Dr. Sophie PAGET-BAILLY, Pr. Franck BONNETAIN
Journal name : Cancer Medecine

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AbstractTemozolomide (TEM) showed encouraging results in well-differentiated pancreatic neuroendocrine tumors (WDPNETs)....

Posted by : Dr. Dewi VERNEREY
Journal name : Endocrine-Related Cancer

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AbstractThe diagnosis system for allograft loss lacks accurate individual risk stratification on the basis of...

Posted by : Dr. Dewi VERNEREY
Journal name : J Am Soc Nephrol

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In first-line metastatic colorectal cancer (mCRC), baseline prognostic factors allowing death risk and treatment...

Posted by : Dr. Dewi VERNEREY, Pr. Franck BONNETAIN
Journal name : International Journal of Cancer

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Background:The management of locally advanced pancreatic cancer (LAPC) patients remains controversial. Better...

Posted by : Dr. Dewi VERNEREY, Pr. Franck BONNETAIN
Journal name : British Journal of Cancer

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Our aim was to review the studies which assessed potential surrogate endpoints for overall survival (OS) in breast...

Posted by : Pr. Franck BONNETAIN,
Journal name : Breast

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In the Intergroupe Francophone de Cancérologie Thoracique 0501 trial the carboplatinpaclitaxel chemotherapy increased...

Posted by : , Dr. Amélie ANOTA, Pr. Franck BONNETAIN
Journal name : European Respiratory Journal

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Background: Even though the perioperative chemotherapy improves the overall survival (OS) compared to surgery alone in...

Posted by : Dr. Sophie PAGET-BAILLY, , Pr. Franck BONNETAIN
Journal name : European Journal of Surgical Oncology

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PurposeWe previously showed that a sequential chemotherapy with dose-dense oxaliplatin (FOLFOX7)and irinotecan (FOLFIRI;...

Posted by : Pr. Franck BONNETAIN
Journal name : PLOS ONE

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AbstractGlioblastoma is the most common malignant brain tumor in adults. Baselinehealth-relatedquality of life (HRQoL)...

Posted by : , Dr. Dewi VERNEREY, Dr. Amélie ANOTA, Pr. Franck BONNETAIN
Journal name : Cancer Medicine

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OBJECTIVES: The objective of this study was to explore the association between health-related quality of life (HRQoL)...

Posted by : Dr. Amélie ANOTA, Pr. Franck BONNETAIN
Journal name : BMJ Open

OBJECTIVES: We conducted a prospective study approved by the local ethics committee to determine the impact of a...

Posted by : Dr. Amélie ANOTA, Pr. Franck BONNETAIN
Journal name : Annales pharmaceutiques françaises

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IMPORTANCE In locally advanced pancreatic cancer, the role of chemoradiotherapy is controversial and the efficacy of...

Posted by : Pr. Franck BONNETAIN
Journal name : JAMA

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Health-related quality of life (HRQOL) in cancer research is critical to more comprehensively evaluate patients’...

Posted by : Pr. Franck BONNETAIN, , Dr. Amélie ANOTA
Journal name : Journal of Clinical Oncology

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AbstractBackground: Health-related quality of life (HRQoL) is recognized as a component endpoint for cancer...

Posted by : , Dr. Amélie ANOTA, Pr. Franck BONNETAIN
Journal name : BMC Cancer

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Background: Deficient mismatch repair (dMMR) colon cancer (CC) is reportedly resistant to 5-fluorouracil (5FU) adjuvant...

Posted by : Dr. Guillaume MOUILLET, Dr. Dewi VERNEREY, Pr. Franck BONNETAIN
Journal name : JNCI Journal of the National Cancer Institure

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AbstractBACKGROUND:We investigated whether the health-related quality of life (HRQoL) score is a prognostic factor for...

Posted by : , Dr. Dewi VERNEREY, Pr. Franck BONNETAIN
Journal name : EJC

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Purpose Eastern Cooperative Oncology Group Performance Status (ECOG-PS) is currently an important parameter in the...

Posted by : Pr. Franck BONNETAIN
Journal name : Quality of Life Research

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AbstractPURPOSE:The MOSAIC (Multicenter International Study of Oxaliplatin/Fluorouracil/Leucovorin in the Adjuvant...

Posted by : Dr. Dewi VERNEREY, Pr. Franck BONNETAIN
Journal name : JCO

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AbstractBACKGROUND:The combination of an anti-VEGF or an anti-EGFR-targeted monoclonal antibody with chemotherapy has...

Posted by : Dr. Dewi VERNEREY, Pr. Franck BONNETAIN
Journal name : Lancet Oncol

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AbstractOBJECTIVES:To assess the long term outcomes of transplantation using expanded criteria donors (ECD; donors aged...

Posted by : Dr. Dewi VERNEREY
Journal name : BMJ

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ABSTRACT Rationale:The role of circulating antibodies in addition to traditional cardiovascular risk factors in...

Posted by : Dr. Dewi VERNEREY
Journal name : Test

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AbstractAIM:Microarray studies identified a subgroup of molecular apocrine tumors (estrogen receptor [ER]...

Posted by : Dr. Dewi VERNEREY
Journal name : Future Oncol

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Abstract Background: Baseline prognostic biomarkers stratifying treatment strategies in first-line metastatic...

Posted by : Pr. Franck BONNETAIN, Dr. Dewi VERNEREY
Journal name :

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AbstractOverall survival (OS) has been considered as the most relevant primary endpoint but trials using OS often...

Posted by : , , Dr. Amélie ANOTA, Dr. Dewi VERNEREY, Dr. Sophie PAGET-BAILLY, Pr. Franck BONNETAIN
Journal name : Expert Review of Anticancer Therapy

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BACKGROUND:A randomized multicenter phase II trial was conducted to assess the sequential treatment strategy using...

Posted by : Dr. Amélie ANOTA, Dr. Guillaume MOUILLET, Dr. Sophie PAGET-BAILLY, Pr. Franck BONNETAIN
Journal name : PlosOne

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AbstractBACKGROUND:The incidence of anal squamous cell carcinoma has been increasing markedly in the past few decades....

Posted by : Dr. Amélie ANOTA, Mme. Aurélia MEURISSE, Dr. Dewi VERNEREY
Journal name : Lancet Oncol

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