The Methodology and Quality of Life Unit in Oncology was set up in 2011 at the University Hospital of CHU Besançon to help and develop the clinical research activity, mainly in the field of oncology.


Project
    The Methodology and Quality of Life Unit in Oncology (UMQVC) offers methodological expertise for the construction of clinical trials and epidemiological studies using the most appropriate validated tools. Our philosophy is to provide the methodological rigor required for quality clinical research while keeping the benefit of the patient as a priority. Our national and international collaborations allow us to widely share our vision and expertise. The entire team, clinical research associates, data managers, statistician/epidemiologists and specialized physicians, works to promote the idea that the patient should be at the center of research and that "cancer is not just a tumor".

Team structure
    The UMQVC is a functional unit of the oncology department affiliated to the UMR INSERM 1098. Its main research thematics are prognostic research, Health Related Quality of Life (QoL) research and QoL assessment in daily clinical practice.

    The UMQVC, was launched in 2011 by Professor Franck BONNETAIN. In 2017 3 modules emerged:
        - Epidemiology and Biostatistics (module 1, Dr Dewi VERNEREY)
        - Methodological research in QoL (module 2, Dr Amélie ANOTA)
        - QoL monitoring in routine (module 3, Dr Sophie PAGET-BAILLY)

    Since January 2018 and following the sad loss of Franck, Professor Virginie WESTEEL is responsible for the team and the UMQVC becomes a functional unit of the oncology department.

    Module 1 is member and the methodological referent for the GERCOR (national oncology cooperative group, whose data processing center is labeled by the French National Cancer Institute). He is also a member of the ARCAD Foundation and HalioDX scientific boards. Its own research theme is the statistical methodology development in risk prediction and stratification to provide tools to adapt patient's management and to guide research strategies. This module works also with AGEO and FRENCH groups. The module is the European referent for the analysis of the metastatic colorectal cancer meta-base of the ARCAD foundation. At the University Hospital of Besançon, most of its collaborations involve oncology, nephrology and digestive surgery departments.

    Module 2 is member of the National QoL and Cancer Platform and of the EORTC QOL Group. He is also the referent for the QoL methodology of 2 national cooperative groups (AFSOS Unicancer, ARCAGY Gineco) and participates in the expert comitee in adapted physical activity within AFSOS. Its own research theme is the development of tools for the QoL data analysis in oncology clinical trials. He also develops collaborative projects in human and social sciences and medico-economic about the QoL of patients and caregivers. At the University Hospital of Besançon, most of its collaborations involve oncology, anesthesia and surgical resuscitation departments. The module also collaborates closely with PGI.

    Module 3 coordinates the research activity on the routine QoL monitoring. The goal is to use QoL information as a complementary tool in the management of cancer patients. To date, more than 300 patients with 5 cancer sites (gynecological, colorectal, lung, breast and kidney) are included. The module collaborates with the team developing the CHES, the oncology and gynecology departments of the University Hospital of Besançon and the Besançon psychology laboratory of the UBFC.

    In addition, the UMQVC also provides statistical expertise for the Cochrane Lung Cancer Group.

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